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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>International Journal of Pharmacognosy and Herbal Drug Technology</journal-title>
        <abbrev-journal-title abbrev-type="publisher">IJPHDT</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">3049-1630</issn>
      <publisher>
        <publisher-name>Dr. Arpan Kumar Tripathi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.64063/3049-1630.vol.2.issue12.1</article-id>
      <article-id pub-id-type="publisher-id">ijphdt-00000205</article-id>
      <title-group>
        <article-title>Efficacy And Safety of Herbal Mouthwashes in Preventing Gingivitis: A Multi-Center Randomized Trial</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Kumar</surname>
            <given-names>Lokesh Kumar</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Patankar</surname>
            <given-names>Ashutosh </given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Verma</surname>
            <given-names>Aditi Verma</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Bhaskar</surname>
            <given-names>Khushboo </given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Rajput</surname>
            <given-names>Rahul Singh </given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">SSIPSR, Shri Shankaracharya Professional University, Chhattisgarh, India</aff>
      <pub-date pub-type="epub" iso-8601-date="2026">
        <year>2026</year>
      </pub-date>
      <volume>2</volume>
      <issue>12</issue>
      <abstract>
        <p>
 

There is a need for efficient and well-tolerated preventive strategies for gingivitis because it is one of the most common inflammatory disorders impacting oral health. This 4-week randomized clinical experiment compared chlorhexidine, an anti-gingival mouthwash, to a herbal mouthwash to see which was more effective and safer. At baseline, 2 weeks, and 4 weeks after treatment, 120 people with mild to moderate gingivitis were evaluated clinically; those in the chlorhexidine group were compared to those in the herbal group. At the conclusion of the intervention, there was no statistically significant difference between the two groups, and both groups showed substantial reductions in Gingival Index and Plaque Index scores. On the other hand, the herbal mouthwash was much more tolerable, with far less side effects. These results indicate that herbal remedies can be a safer and more efficient substitute for chlorhexidine in the treatment of gingivitis and in enhancing the results of dental hygiene routines.</p>
      </abstract>
      <kwd-group kwd-group-type="author">
        <kwd>Ex Vivo Permeation.</kwd>
        <kwd>In Vitro Dissolution</kwd>
        <kwd>Targeted Intestinal Delivery</kwd>
        <kwd>Curcuma Longa</kwd>
        <kwd>Gymnema Sylvestre</kwd>
        <kwd>Herbal Medicine</kwd>
        <kwd>Enteric-Coated Tablets</kwd>
      </kwd-group>
    </article-meta>
  </front>
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